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Seek emergency medical attention. What should I avoid while taking pyrantel? Disclaimer: Every effort has been made to ensure that the information provided is accurate, up-to-date and complete, but no guarantee is made to that effect. In addition, the drug information contained herein may be time sensitive and should not be utilized as a reference resource beyond the date hereof. This material does not endorse drugs, diagnose patients, or recommend therapy. Broad Spectrum Wormer tablets will remove Tapeworms Dipylidium caninum, Taenia taeniaeformis Hookworms Ancylostoma tubaeforme and Large Roundworms Toxocara cati in kittens and cats. generic careprost dosages

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Tablets for removal of E. multilocularis is the same as that indicated for the removal of the other tapeworm species listed on the label. Laboratory efficacy studies conducted with Drontal Plus tablets have demonstrated the recommended dosage is 100% effective. The original geographic distribution of E. multiloculariswas primarily confined to northern areas of North America. Current evidence indicates migration of the parasite well into the continental United States. Additional information on the life cycle and epidemiology of this parasite is available in veterinary parasitology texts. Hookworms are small whitish or reddish-brown worms less than one inch in length that live in the intestinal tract and feed on blood. Cats can become infected with hookworms by swallowing infected larvae while grooming or when larvae from the environment burrow through the skin. Cats infected with hookworms may have poor physical condition, dull haircoat, and reduced body weight and diarrhea, sometimes with the presence of dark blood.

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Animals Using a Biological Assay. Echinococcus multilocularisis a tapeworm species usually found in wild canids, including foxes, coyotes and wolves. The parasite has also been identified in domestic dogs and cats and is potentially a serious public health concern because it may infect humans. Store at or below 77ºF 25ºC.

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One dog receiving a 3 times labeled dose had elevated SGPT, SGOT, CPK and GGT readings outside of normal range at 6 days post-treatment. Subcutaneous injection can cause a transient local tissue reaction that may result in trim loss of edible tissue at slaughter. Safety Study in Heartworm Positive Cats: Cats artificially infected with adult heartworms harvested from dogs were treated topically with Profender Topical Solution at 0X, 1X or 5X the recommended dose once a month for three treatments. Clinical signs included salivation one 1X and three 5X cats labored breathing all groups and lethargy one 5X cat. At the study conclusion, the 1X and 5X cats had fewer live heartworms recovered than the 0X group.



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Take the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not take extra medicine to make up the missed dose. What happens if I overdose? Broad Spectrum Chewable Anthelmintic Tablets are indicated for removal of Tapeworms Dipylidium caninum, Taenia pisiformis, Echinococcus granulosus, and removal and control of Echinococcus multilocularis and for removal of Hookworms Ancylostoma caninum, Uncinaria stenocephala Ascarids Toxocara canis, Toxascaris leonina and Whipworms Trichuris vulpis in dogs. Large roundworms and hookworms may be observed in the feces of the cat a day or so after the cat has been treated with Drontal Tablets. The majority of tapeworms, however, are digested and are not found in the feces after treatment. Freedom of Information Summary FOI NADA 133-953 Vercom Paste febantel and praziquantel. Plus Anthelmintic Tablets in the clinical field studies exhibited drug-related side effects. Do not apply to broken skin or if hair coat is wet. You should not take this medicine if you are allergic to praziquantel, or if you have take rifampin Rifadin, Rifater, Rifamate in the last 4 weeks. Not for human use. Keep out of reach of children. If reinfection with tapeworms, hookworms or large roundworms occurs, treatment with Drontal Tablets may be repeated. Cats maintained under conditions of constant exposure to parasite infections should have a follow-up fecal exam within 2 to 4 weeks after the first treatment. Always consult a healthcare professional for medical advice. Tablets and dogs treated at intervals greater than 28 days may shed eggs in the feces after treatment. The animal should be held in the clinic during this interval and all feces should be incinerated or autoclaved.



Store at or below 77ºF 25ºC

Praziquantel should be taken with a meal. The presence of tapeworms is indicated by the observance of tapeworm segments passed in the cat's feces. Tapeworm segments are white, pinkish-white or yellow-white in colour and are similar in size and shape to flattened grains of rice. The segments are most frequently observed lying on a freshly passed stool. Segments may also be found on the hair around the anus of the animal, or on the animal's bedding. Cats become infected with tapeworms after eating fleas or small animals mice and other rodents which may be infected with tapeworm larvae. Cats become infected with large roundworms by swallowing infective eggs, particularly while grooming, or by ingestion of mice that may be infected with larval stages. Symptoms of overdosage 33. Do not administer to weak or debilitated animals. Do not administer this drug to breeding animals or to animals kept for breeding purposes. There are no known contraindications against the use of praziquantel or pyrantel pamoate in dogs. Stelma FF, Talla I, Sow S, Kongs A, Niang M, Polman K, Deelder AM, Gryseels B "Efficacy and side effects of praziquantel in an epidemic focus of schistosoma mansoni. pioglitazone



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To prevent reinfection, toilets must be disinfected daily, and clothing, linens, towels, and pajamas must be changed and washed daily. Praziquantel may also be used for purposes not listed in this medication guide. What is the most important information I should know about praziquantel? Plus Tablets are safe and efficacious for the removal of the parasite species indicated on the label when used as directed. Polderman AM, Gryseels B, Gerold JL, Mpamila K, Manshande JP "Side effects of praziquantel in the treatment of Schistosoma mansoni in Maniema, Zaire. Bayer, the Bayer Cross, and Baytril are trademarks of Bayer. F; however such exposure should be minimized. Ciferri F "Delayed CSF reaction to praziquantel. Roundworms and hookworms are controlled by maintaining the cat's environment free of infective eggs and larvae. Feces and soiled litter should be removed on a daily basis to prevent build-up of eggs and larvae in the environment. F. Precipitation may occur due to cold temperature. To redissolve, warm and then shake the vial. Since pyrantel is usually taken in one dose, you are not likely to miss a dose. What happens if I overdose? Plus Tablets contain three active ingredients having different modes of action and spectra of activity. Praziquantel is active against cestodes tapeworms. Praziquantel is absorbed, metabolized in the liver and excreted in the bile. Upon entering the digestive tract from the bile, cestocidal activity is exhibited. 1 Following exposure to praziquantel, the tapeworm loses its ability to resist digestion by the mammalian host. Because of this, whole tapeworms, including the scolices, are very rarely passed after administration of praziquantel. In many instances only disintegrated and partially digested pieces of tapeworms will be seen in the stool. The majority of tapeworms are digested and are not found in the feces. Of those, 606 received a single treatment with Profender Topical Solution. McMahon JE "Praziquantel: a new schistosomicide against Schistosoma mansoni. Dogs infected with E. multilocularis should be treated to prevent exposure of humans to infective eggs and to reduce perpetuation of the parasite's life cycle. buy spiriva pharmacy canada spiriva



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Taste Tabs information published above. However, it remains the responsibility of the readers to familiarize themselves with the product information contained on the US product label or package insert. Tablets contain three active ingredients having different modes of action and spectra of activity. Praziquantel is active against cestodes tapeworms. Praziquantel is absorbed, metabolized in the liver and excreted in the bile. Upon entering the digestive tract from the bile, cestocidal activity is exhibited. Available in bottles of 50 tablets. Hepatosplenic schistosomiasis patients with moderate to severe liver dysfunction Child-Pugh B and C: Usual dose should be used with caution. Broad Spectrum Anthelmintic Tablets are available in three sizes. Each size is scored for convenient oral administration. Regulations for product use are established by country. Information contained on this site pertains only to the United States of America, and is not intended to provide adequate information for product use. Before using or dispensing any product, read and carefully observe the label directions. Plus Tablets demonstrate that each of the three active ingredients act independently without interference. The combined tablet formulation provides a wide spectrum of activity against the indicated species of intestinal helminths. Homeida MM, Eltom IA, Sulaiman SM, Ali HM, Bennett JL "Tolerance of two brands of praziquantel. Store at room temperature away from moisture and heat. What happens if I miss a dose? Tell your doctor all medications you use. During pregnancy, Biltricide should be used only when prescribed. This drug passes into breast milk. Breastfeeding while using this drug is not recommended. Nursing mothers should stop breastfeeding on the day of treatment and for 72 hours after taking the last dose. To prevent accidental ingestion of the product, children should not come in contact with the application site for twenty-four 24 hours while the product is being absorbed. Pregnant women, or women who may become pregnant, should avoid direct contact with, or wear disposable gloves when applying, this product. Studies performed in rats and rabbits suggest that emodepside may interfere with fetal development in those species. Consult WARNINGS section for additional precautions. Large roundworms are white or yellow-white strands 2-7 inches in length similar in size and colour to smooth strings of spaghetti that may be observed in the cat's vomit or feces. Cats become infected with large roundworms by swallowing infective eggs, particularly while grooming, or by ingestion of mice that may be infected with larval stages. Do not drive or operate heavy machinery on the day of and during the 24 hours after treatment; the drug may cause dizziness or drowsiness. There were no clinical signs of toxicity or pathological changes. amlodipine airport



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Grapefruit and grapefruit juice may interact with praziquantel and lead to potentially dangerous effects. Discuss the use of grapefruit products with your doctor. Drontal, Bayer and Bayer Cross are registered trademarks of Bayer AG, used under license. Repeat dose in 2 weeks. Each tablet size is available in bottles of 50 puppies and small dogs, medium sized dogs or 30 large dogs. Praziquantel is an anthelmintic an-thel-MIN-tik or anti-worm medication. It prevents newly hatched insect larvae worms from growing or multiplying in your body.



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Our Biltricide praziquantel Side Effects Drug Center provides a comprehensive view of available drug information on the potential side effects when taking this medication. Hookworms are small whitish or reddish-brown worms less than one inch in length that live in the intestinal tract and feed on blood. Cats can become infected with hookworms by swallowing infective larvae while grooming or when larvae from the environment burrow through the skin. Cats infected with hookworms may have poor physical condition, dull haircoat, reduced body weight and diarrhea, sometimes with the presence of dark blood. DO NOT USE IN PREGNANT ANIMALS. Dogs treated with elevated levels 6 consecutive days with 3 times the labeled dosage rate of the combination of febantel and praziquantel in early pregnancy demonstrated an increased incidence of abortion and fetal abnormalities. Tablets in a clinical field study did not exhibit any drug related side effects. A temporary loss of appetite was reported for one cat and transient loose stools were observed in a second cat. Mazzotti reaction after treatment with ivermectin, praziquantel, and albendazole for presumptive schistosomiasis and strongyloidiasis. Six days after receiving standard empiric therapy, he developed epigastric pain, vomiting, and urticaria. This progressed in 4 hours and included fever, general myalgia, and edema of the face, lower extremities, and penis accompanied by urticaria of the arms, legs, and trunk. He was diagnosed with a Mazzotti reaction and treated with methylprednisolone; symptoms subsided within 12 hours. An injection site study conducted in feeder calves demonstrated that the formulation may induce a transient reaction in the subcutaneous tissue and underlying muscle. No painful responses to administration were observed. Tapeworm segments are white, pinkish-white or yellow-white in color and are similar in size and shape to flattened grains of rice. The segments are most frequently observed lying on a freshly passed stool. Diagnosis of E. multilocularis in canids is difficult. The adult tapeworm produces no clinical signs of infection. Tapeworm segments proglottids are usually not observed in the feces. E. multilocularis eggs, observed using microscopic fecal examination procedures, are similar in appearance to those of common species such as Taenia pisiformis. Assistance in the diagnosis of E. multilocularismay be available from a state veterinary diagnostic laboratory. The original geographic distribution of E. multilocularis was primarily confined to northern areas of North America. Current evidence indicates migration of the parasite well into the continental United States. order generic spirotone online shop



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Dose Tolerance Study in Cats: Profender Topical Solution was applied topically one time to young cats at 10X the recommended label use rate. Two cats salivated. Another cat exhibited tremors and lethargy. These signs were self-limiting. When schistosomiasis or fluke infection is associated with cerebral cysticercosis, hospitalization of the patient for the duration of therapy is recommended. Side effects included malaise, headache, dizziness, abdominal discomfort with or without nausea rise in temperature, and urticaria; generally in order of severity. Bayer, the Bayer Cross, and Drontal are registered trademarks of Bayer. Before taking praziquantel, tell your doctor if you have kidney disease, heart disease, liver disease, or a history of seizures or epilepsy. Consult your veterinarian before administering to sick or pregnant animals. Do not keep tablets or portions of tablets in your mouth; the bitter taste may cause gagging or vomiting. Disclaimer: Every effort has been made to ensure that the information provided by Cerner Multum, Inc. 'Multum' is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Multum's drug information does not endorse drugs, diagnose patients or recommend therapy. Carbatrol, Equetro, Tegretol felbamate Felbatol oxcarbazepine Trileptal or phenytoin Dilantin or primidone Mysoline. The adult tapeworm is small 1-4mm and resides in the intestinal tract of the definitive host wild or domestic canids. Eggs from the adult tapeworm are shed in the feces of the infected canid. Rodents such as mice and voles serve as the intermediate host for E. multilocularis. Eggs ingested by rodents develop in the liver, lungs and other organs to form multilocular cysts. The life cycle is completed after a canid consumes a rodent infected with cysts. After ingestion of the infected rodent, larvae within the cyst develop to adult tapeworms in the intestinal tract of the canid. Eggs may begin to be passed in the feces of the canid approximately 28 days later. F was statistically significantly greater than the success rate of saline-treated “sick and febrile” pigs. For the control of SRD, mean rectal temperature, mortality one trial and morbidity were statistically significantly lower for enrofloxacin-treated pigs in pens containing a percentage of “sick and febrile” pigs compared to saline-treated pigs. Watt G, Baldovino PC, Castro JT, Fernando MT, Ranoa CP "Bloody diarrhoea after praziquantel therapy. Pyrantel may be taken with or without food at any time of the day. vidf.info progynova



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Swallow tablets or portions of tablets whole without chewing; take with water during meals. Cerner Multum, Inc. "Australian Product Information. Praziquantel is usually taken 3 times in one day. Your doses should be taken 4 to 6 hours apart on that day. Domestic dogs living in E. multilocularis endemic areas that roam freely with the opportunity to catch wild rodents are at risk of infection. Pet owners should be advised on how to minimize this risk. Some praziquantel side effects may not need any medical attention. As your body gets used to the medicine these side effects may disappear. Bayer, the Bayer Cross, and Drontal are trademarks of Bayer. All areas where the animal was maintained or in contact with should be thoroughly cleaned with sodium hypochlorite and allowed to dry completely before reuse. The tablets were offered free-choice to the dogs by their owners and over 89% of the dogs willingly consumed the tablets. Praziquantel is also used to treat infection with liver flukes, caused by a type of worm found in East Asia. This worm enters the body while eating contaminated fish. Strict hygienic precautions should be taken when handling dogs or feces suspected of harboring E. multilocularis. Steps should be taken to prevent parasite infections otherwise retreatment will be necessary. The daily dose has been given in 3 divided doses. hydrochlorothiazide



Praziquantel is an isoquinoline cestocide

Cats treated with 10 times the highest recommended Drontal dosage during safety studies showed signs of vomition and salivation without other adverse effects. Eighty-three of 85 cats treated with the recommended dosages of Drontal Tablets in a clinical field study did not exhibit any drug related side effects. A temporary loss of appetite was reported for one cat and transient loose stools were observed in a second cat. The recommended dosage of praziquantel is not affected by the presence or absence of food in the gastrointestinal tract, therefore, FASTING IS NEITHER NECESSARY NOR RECOMMENDED. Domestic dogs living in E. multilocularisendemic areas that roam freely with the opportunity to catch wild rodents are at risk of infection. Pet owners should be advised on how to minimize this risk. Every effort has been made to ensure the accuracy of the Drontal information published above. However, it remains the responsibility of the readers to familiarize themselves with the product information contained on the Canadian product label or package insert. Other, less serious side effects may be more likely to occur. Cats maintained under conditions of constant exposure to parasite infections should have a follow-up fecal examination within 2 to 4 weeks after the first treatment. Plus Tablets for removal of E. multilocularis is the same as that indicated for the removal of the other tapeworm species listed on the label. Laboratory efficacy studies have demonstrated the recommended dosage is 100% effective. Tapeworms transmitted by fleas will likely recur unless measures are taken to control fleas. Product Information. Biltricide praziquantel. RETREATMENT: Steps should be taken to prevent parasite infections, otherwise retreatment will be necessary. Do not take other anti-worm medicines at the same time as pyrantel unless otherwise directed by your doctor. Other drugs used to treat infections caused by worms may decrease the effectiveness of pyrantel. Drugs other than those listed here may also interact with pyrantel. Talk to your doctor and pharmacist before taking any prescription or over-the-counter medicines. Domestic dogs living in E. multilocularis endemic areas that roam freely with the opportunity to catch wild rodents are at risk for infection. Pet owners should be advised on how to minimize this risk. Proper restraint of roaming dogs should be encouraged, along with regular treatment with Droncit Injectable solution, following the dosing schedule aforementioned and precautions indicated below. The long-term effects on articular joint cartilage have not been determined in pigs above market weight. Broad Spectrum Chewable Anthelmintic Tablets for Dogs are available in three tablet sizes. Each size is scored for convenient oral administration. Plus Anthelmintic Tablets. In addition, 103 dogs and puppies were included in clinical field studies conducted in 5 veterinary clinics at different geographic locations throughout the United States to further evaluate safety and efficacy. These studies included dogs of various sizes, ages and breeds. Data from these studies demonstrated Drontal Plus Anthelmintic Tablets are safe and efficacious for the removal of the parasite species indicated on the label when used as directed.



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The time interval between individual doses should not be less than 4 hours and not more than 6 hours. The adult tapeworm is small 1-4mm and resides in the intestinal tract of the definitive host wild or domestic canids. Eggs from the adult tapeworm are shed in the feces. Rodents such as mice and voles serve as the intermediate host. Eggs ingested by rodents develop in the liver, lungs and other organs to form multilocular cysts. The life cycle is completed after a canid consumes a rodent infected with cysts. Larvae within the cyst develop into adult tapeworms in the intestinal tract of the canid. Plus Tablets, following the dosing schedule aforementioned and precautions indicated below. Some pyrantel side effects may not need any medical attention. As your body gets used to the medicine these side effects may disappear. Lieby PD, Carney WP and Woods CE. 1970. Studies on Sylvatic Echinococcosis. III. Host Occurrence and Geographic Distribution of Echinococcus multilocularis in the North Central United States. J Parasit 56 6 1141-1150. Tablets, following the dosing schedule aforementioned and precautions indicated below. The effectiveness of this product when used before bathing has not been evaluated. Emodepside, a semi-synthetic molecule, is a cyclic depsipeptide. Lieby PD, Carney WP and Woods CE. 1970. Studies on Sylvatic Echinococcosis, Ill. Host Occurrence and Geographic Distribution of Echinococcus multilocularis in the North Central United States. J. Parasit. 566: 1141-1150. Craig PS and McPharson CNL. 1988. Sodium Hypochlorite as an Ovicide for Echinococcus. Ann Trop Med. and Parasit. 822: 211-213. Febantel is active against nematode parasites including whipworms. Febantel is rapidly absorbed and metabolized in the animal. Data from these studies demonstrated Profender Topical Solution is safe and effective for the treatment and control of hookworm infections caused by Ancylostoma tubaeforme adults, immature adults, and fourth stage larvae roundworm infections caused by Toxocara cati adults and fourth stage larvae and tapeworm infections caused by Dipylidium caninum adults and Taenia taeniaeformis adults. does lloyds isoxsuprine



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Repeat dose twice at 2 weeks intervals. What other drugs will affect pyrantel? Foreign Market Experience: The following adverse events were reported voluntarily during post-approval use of the product in foreign markets: application site reaction hair loss, dermatitis, pyoderma, edema, and erythema salivation, pruritus, lethargy, vomiting, diarrhea, dehydration, ataxia, loss of appetite, facial swelling, rear leg paresis, seizures, hyperesthesia, twitching, and death. Droncit praziquantel has been tested in breeding and pregnant dogs and cats. No adverse effects were noted. Steps should be taken to prevent parasite infections, otherwise retreatment will be necessary. An injection site study conducted in pigs demonstrated that the formulation may induce a transient reaction in the subcutaneous tissue. No painful responses to administration were observed. Roundworms and hookworms are controlled in cats by maintaining an environment free of infective eggs and larvae. Feces and soiled litter should be removed on a daily basis to prevent build-up of eggs and larvae in the environment. Enrofloxacin is bactericidal and exerts its antibacterial effect by inhibiting bacterial DNA gyrase a type II topoisomerase thereby preventing DNA supercoiling and replication which leads to cell death. 1 Enrofloxacin is active against Gram-negative and Gram-positive bacteria. Consult your veterinarian for assistance in the diagnosis, treatment and control of parasites. Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat. colospa



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The effects of enrofloxacin on cattle or swine reproductive performance, pregnancy and lactation have not been adequately determined. Cats become infected with tapeworms after eating fleas or small mammals rabbits, mice which may be infected with tapeworm larvae. There are no known contraindications to the use of praziquantel. buy now inderal online europe

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KEEP OUT OF REACH OF CHILDREN. Consult your veterinarian before administering to sick or pregnant animals. Tablets are safe and efficacious for the removal of the parasite species indicated on the label when used as directed. Safety has not been established in patients younger than 4 years. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist. aricept

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The life cycle of the parasite is based on a predator-prey relationship as depicted. Quinolone-class drugs should be used with caution in animals with known or suspected Central Nervous System CNS disorders. In such animals, quinolones have, in rare instances, been associated with CNS stimulation which may lead to convulsive seizures. Quinolone-class drugs have been shown to produce erosions of cartilage of weight-bearing joints and other signs of arthropathy in immature animals of various species. See Animal Safety section for additional information. Dermatologic side effects have included skin rashes.

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KEEP OUT OF REACH OF CHILDREN. Hildreth MB Johnson MD and Kazacos KR. 1991. A Zoonosis of Increasing Concern in the United States. Compendium for Cont. Ed. 135: 727-740. ECHINOCOCCUS MULTILOCULARIS: Echinococcus multilocularis is a tapeworm species usually found in wild canids, including foxes, coyotes and wolves. The parasite has also been identified in domestic dogs and cats and is potentially a serious public health concern because it may infect humans.

Post-Approval Experience: Although not all adverse reactions are reported, based on voluntary post-approval reporting, transient ataxia has been reported following the administration of Drontal Tablets for Cats and Kittens. Large roundworms are white or yellow-white strands 2-7 inches in length similar in size and color to smooth strings of spaghetti that may be observed in the cat's vomit or feces. Cats become infected with large roundworms by swallowing infective eggs, particularly while grooming, or by ingestion of mice that may be infected with larval stages. Craig PS and McPharson CNL. 1988. Sodium Hypochlorite as an Ovicide for Echinococcus. Ann Trop Med and Parasit 822 211-213.

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